abstract：:The currently available interventional cardiac procedures in neonates and infants are at various stages of development. We currently dilate neonates and infants with critical valvular pulmonary and aortic stenosis and postoperative aortic obstruction. We do not routinely dilate native coarctation of the aorta because ...

journal_title：Clinics in perinatology

authors： Zeevi B,Perry SB,Keane JF,Mandell VS,Lock JE

更新日期：1988-09-01 00:00:00

abstract：:Most pharmacokinetic and biologic attributes of digitalis are age dependent. They are determined in great measure by the chemical structure of the specific cardiac glycoside being used. These effects differ in the intact normal circulation and in heart failure because of the altered autonomic nervous system and hormon...

journal_title：Clinics in perinatology

authors： Hastreiter AR,John EG,van der Horst RL

更新日期：1988-09-01 00:00:00

abstract：:Fetal and neonatal infections can occur at different times during pregnancy, from conception to birth. Infections that take place near the time of conception often destroy the zygote or embryo and only rarely leave definitive evidence. The mother can transmit the infection to her fetus through several routes, but the ...

journal_title：Clinics in perinatology

authors： Zeichner SL,Plotkin SA

更新日期：1988-06-01 00:00:00

abstract：:Twins have higher rates of perinatal mortality, prematurity and its complications, low birth weight, intrauterine growth retardation, congenital anomalies, and long-term developmental morbidity. Monozygotic twins have lower birth weights and higher rates of congenital anomalies than dizygotic twins, which suggests tha...

journal_title：Clinics in perinatology

authors： McCulloch K

更新日期：1988-03-01 00:00:00

abstract：:The newborn infant's skin is not a complete barrier to the absorption of externally applied agents, particularly if it is damaged, diseased, or immature. Immaturity is the most important factor that determines percutaneous absorption. Very immature infants in the early neonatal period have a poorly developed epidermis...

journal_title：Clinics in perinatology

authors： Rutter N

更新日期：1987-12-01 00:00:00

abstract：:Beta-sympathomimetic agents are used extensively in obstetrics to inhibit premature labor. Knowledge of the pharmacology, mode of action on smooth muscle, and cardiovascular and metabolic side effects of these agents is essential for the obstetrician and perinatologist. This review article draws extensively on recent ...

journal_title：Clinics in perinatology

authors： Nuwayhid B,Rajabi M

更新日期：1987-12-01 00:00:00

abstract：:HFV is a mode of therapy that allows gas exchange with pressure fluctuations much lower than that required for conventional ventilation, and may consequently decrease the incidence of barotrauma and chronic lung disease. At present the National Institute of Health is sponsoring the first large controlled trial to test...

journal_title：Clinics in perinatology

authors： Bancalari E,Goldberg RN

更新日期：1987-09-01 00:00:00

abstract：:The past 15 years has seen the resurgence of an interest in biomedical ethics and an awareness of the importance of teaching this discipline in medical curricula at varying levels. Physicians and philosophers can work together to achieve an integration of clinical case material and philosophical theory, in order to te...

journal_title：Clinics in perinatology

authors： Fleischman AR,Arras J

更新日期：1987-06-01 00:00:00

abstract：:The Mothers' Milk Bank (MMB) of San Jose, CA, has provided banked human milk to clinicians and researchers since its founding in 1974. This article briefly acknowledges the many and varied reasons for the use of human milk. Its primary focus however, is to review the protocol followed by the MMB for collection, bankin...

journal_title：Clinics in perinatology

authors： Asquith MT,Pedrotti PW,Stevenson DK,Sunshine P

更新日期：1987-03-01 00:00:00

abstract：:Neurologically impaired infants have immature, damaged, or abnormally developed nervous systems that may cause abnormalities of sucking and swallowing, among other problems. Sucking abnormalities usually present as absence of the sucking response, weakness or incoordination of sucking and swallowing, or some combinati...

journal_title：Clinics in perinatology

authors： McBride MC,Danner SC

更新日期：1987-03-01 00:00:00

abstract：:The development of the flow-directed pulmonary artery catheter in the early 1970s moved invasive monitoring from the laboratory to the patient's bedside. Its current use in obstetrics is directed toward definition of certain pathophysiologic states unique to pregnancy and toward diagnosis and management of critically ...

journal_title：Clinics in perinatology

authors： Hankins GD

更新日期：1986-12-01 00:00:00

abstract：:This study was undertaken to identify the pathologic processes in premature infants weighing less than 1000 gm who require surgery, and the outcome of such operations. These neonates required surgery for NEC and PDA. Congenital anomalies were not encountered in our series. No increased mortality due to surgery was obs...

journal_title：Clinics in perinatology

authors： Lemon DG,Wesselhoeft CW Jr,DeLuca FG

更新日期：1986-06-01 00:00:00

abstract：:Complex biochemical consequences are the result of a series of secondary biochemical changes caused by oxygen depletion. Hypoxia in the fetus and neonate results in decreased GI blood flow, especially to the GI mucosa. Although severe O2 deprivation cannot be entirely compensated for, an increase in tissue O2 extracti...

journal_title：Clinics in perinatology

authors： Goplerud JM,Delivoria-Papadopoulos M

更新日期：1986-03-01 00:00:00

abstract：:Total parenteral nutrition permits normal growth and development of the infant during the adaptive phase of the short bowel syndrome. Skilled nutritional support combined with a variety of medical and surgical manipulations facilitates survival of infants with as little as 15 to 20 cm of intestinal length. ...

journal_title：Clinics in perinatology

authors： Ziegler MM

更新日期：1986-03-01 00:00:00

abstract：:In patients with chronic renal disease, all advice and decisions must take into account the balance between pregnancy outcome and the long-term impact that pregnancy might have on the disease. To help the clinician address these concerns, the authors focus on the renal changes in normal pregnancy, the problems of chro...

journal_title：Clinics in perinatology

authors： Davison JM,Katz AI,Lindheimer MD

更新日期：1985-10-01 00:00:00

abstract：:Numerous articles have chronicled the problems that stem from patients' lack of compliance with health care recommendations, yet there has not been a systematic approach to the development of a strategy for increasing the effectiveness of health education programs. In this article, making use of anticipatory guidance,...

journal_title：Clinics in perinatology

authors： Christophersen ER

更新日期：1985-06-01 00:00:00

abstract：:This chapter describes the utility of event-related potential recordings in the assessment of auditory and visual system integrity in the newborn infant. A battery of electrophysiologic tests is described that permits the evaluation of sequential levels of processing within these sensory system. ...

journal_title：Clinics in perinatology

authors： Kurtzberg D,Vaughan HG Jr

更新日期：1985-02-01 00:00:00

abstract：:This article discusses the background, methodology, previous clinical studies, and the clinical role and limitations of the noninvasive Doppler technique in the assessment of the cerebral circulation of the newborn infant. ...

journal_title：Clinics in perinatology

authors： Perlman JM

更新日期：1985-02-01 00:00:00

abstract：:Pulmonary hypertension in the newborn infant has many potential causes, and multiple etiologies are common. In this article, the author outlines the basic principles in pathophysiology, classification, and etiology that should be well understood by those who care for neonates with disease processes in which pulmonary ...

journal_title：Clinics in perinatology

authors： Gersony WM

更新日期：1984-10-01 00:00:00

abstract：:It is clear that prostaglandins and related compounds are important in the physiology and pathophysiology of the perinatal pulmonary circulation. This article focuses on what is known about prostaglandin-related compounds (PRC) in the pulmonary circulation of the developing and newly born mammal. Also included is a di...

journal_title：Clinics in perinatology

authors： Philips JB 3rd,Lyrene RK

更新日期：1984-10-01 00:00:00

abstract：:Discussed in this article are the effects of pregnancy-induced hypertension on the renin-angiotensin-aldosterone system; the possible role of prostanoids, deoxycorticosterone, and deoxycorticosterone sulfate in blood pressure control; and the effect of pregnancy-induced hypertension upon the endocrinology of the mater...

journal_title：Clinics in perinatology

authors： Carr BR,Gant NF

更新日期：1983-10-01 00:00:00

abstract：:It is now recognized that pregnancy is associated with significant changes in maternal thyroid function that are largely mediated by the placenta. The author summarizes the understanding of these changes during pregnancy and follows with a discussion of fetal thyroid system ontogenesis. ...

journal_title：Clinics in perinatology

authors： Fisher DA

更新日期：1983-10-01 00:00:00

abstract：:Diabetic pregnancies involve complex alterations in maternal-placental and fetal compartments. This article discusses the unique features of diabetic pregnancies as they pertain to the maternal changes that must occur to accommodate the fetus. ...

journal_title：Clinics in perinatology

authors： Hollingsworth DR

更新日期：1983-10-01 00:00:00

abstract：:Nonstress testing appears to be an effective means of identifying fetal condition. Its most definitive benefit is the identification of the "normal" fetus, which often permits a path of nonintervention. A significant benefit of the nonstress test approach is its simplicity and portability which, in a practical sense, ...

journal_title：Clinics in perinatology

authors： Paul RH

更新日期：1982-06-01 00:00:00

abstract：:A regionalized system of perinatal care, which draws on the strengths of individual hospitals and corrects any weaknesses, can enhance the level of performance of the community hospital. Although the care of high risk infants takes priority in this system, concern is expressed that routine perinatal care should also r...

journal_title：Clinics in perinatology

authors： Brown JL

更新日期：1980-03-01 00:00:00

abstract：:Correct fluid and electrolyte concentrations are essential to reduce mortality in critically ill infants. The authors list considerations in calculating the necessary maintenance volumes and emphasize the importance of continuous monitoring of data and a review and retabulation every eight hours, because requirements ...

journal_title：Clinics in perinatology

authors： Bell EF,Oh W

更新日期：1979-03-01 00:00:00

abstract：:Congenital lobar emphysema is an uncommon but potentially life-threatening cause of respiratory distress in the newborn. The clinical picture and radiologic findings are diagnostic. Lobectomy in the distressed neonate is curative. In infants with onset of symptoms between one and four months of age surgery may not be ...

journal_title：Clinics in perinatology

authors： Buckner DM

更新日期：1978-03-01 00:00:00

abstract：:The educational programs that have been developed in newborn special care facilities have two purposes: first, they teach personnel the manual skills that are necessary to manage the sick newborn infant; second, they provide personnel with a better understanding of neonatal pathophysiology so that they can begin to re...

journal_title：Clinics in perinatology

authors： Coen RW

更新日期：1976-09-01 00:00:00

abstract：:The enunciation of equipment requirements has been attempted as needs appear today. Detailed and technical specifications for some of this equipment must be understood prior to major acquisitions. An awareness of current trends in clinical research can often be obtained from appropriate consultants which should forest...

journal_title：Clinics in perinatology

authors： Paul RH

更新日期：1976-09-01 00:00:00

abstract：:A scheme of regionalization is proposed in which a regional perinatal system within a defined geographic area permits access of the high risk mother-fetus and infant to the appropriate level of technology for improved perinatal outcome. ...

journal_title：Clinics in perinatology

authors： Merkatz IR,Johnson KG

更新日期：1976-09-01 00:00:00

abstract：:Familial hypothyroidism results from both thyroidal and extrathyroidal dysfunction. Specific intrathyroidal abnormalities in thyroid hormone synthesis causing goitrous hypothyroidism are iodide trap defect, organification defect, "coupling" defect, iodoprotein defect, and dehalogenase defect. The diagnostic studies fo...

journal_title：Clinics in perinatology

authors： Jackson IM

更新日期：1976-03-01 00:00:00

abstract：:Inherited organic acidemias are a group of metabolic disorders currently being described and investigated as gas-liquid chromatography is applied to unexplained diseases of infancy and childhood. Common clinical presentations include attacks of ketoacidosis, unexplained metabolic acidosis, failure of normal developmen...

journal_title：Clinics in perinatology

authors： Mahoney MJ

更新日期：1976-03-01 00:00:00